
A cryolipolysis fat freezing machine reduces stubborn body fat with controlled cooling: subcutaneous fat cells are more vulnerable to cold than surrounding tissue, so they crystallize and die naturally, then are cleared by the body's metabolism. The Pmise-F01 combines cryo cooling, vacuum suction and infrared light in four handles for non-invasive body contouring without surgery or downtime.
Pmise-F01
A cryolipolysis fat freezing machine is a professional device for non-invasive fat reduction: it cools a vacuum-drawn fold of tissue to a precise set temperature so that fat cells crystallize and die naturally, while skin, nerves and muscle are left unharmed. It is designed for aesthetic clinics, medi-spas and beauty salons that want a measurable, repeatable body contouring treatment, and for distributors seeking a factory-direct supplier. The Pmise-F01 combines controlled cooling from 0 to 15℃, adjustable vacuum suction and infrared light across four handles, so two body areas can be treated symmetrically in one session. Clients typically see the treated bulge flatten progressively over the following weeks as the crystallized fat cells are metabolized away.
Cryolipolysis removes fat by triggering apoptosis - the natural death of fat cells - through precisely controlled cooling. Biologically, the fat cells that reside in the subcutaneous layer are more vulnerable to low temperature than skin, nerves or muscle. The vacuum applicator gently draws the skin fold into the handle, and the cooling plates lower the tissue temperature to a set point between 0 and 15℃. The exposed fat cells crystallize and begin a programmed cell death, while the overlying skin and surrounding tissue remain unharmed.
Over the following weeks the crystallized fat cells are broken down and cleared through the body's metabolism, without adverse effects on liver enzymes or blood fats, so the circumference of the treated area gradually reduces. The Pmise-F01 combines cryo and vacuum with infrared (IR) light, which supports quicker recovery of the treated area after the session. The treatment is programmable and not technique-dependent: once the handles are placed, no staff time is required. For softer, larger fat areas, compare it with our 40KHz ultrasonic cavitation slimming machine, or add the HIFU lifting and contouring system for skin tightening.
Four handles supplied as standard - two pairs specially designed for symmetric treatment, so two areas can be treated in the same session.
Two big LP-L1 handles (165mm*81mm treatment surface) are designed for large-area cryolipolysis such as abdomen and buttocks, improving treatment efficiency.
Two small LP-S1 handles (128mm*57mm treatment surface) are designed for partial and curved areas, ensuring an even slimming effect.
Cryolipolysis combined with infrared light supports quick healing after treatment.
Precise set temperature from 0~15℃, adjustable in steps of 1℃, with water, air and semiconductor cooling for stable long sessions.
User-friendly screen on the handpieces and 12.1 inch color touch LCD on the main unit make operation simple.
These three non-invasive technologies are often shortlisted together, yet they work on different tissue and answer different client requests. The comparison below helps you decide which machine to buy first.
| Technology | Best for | Depth / wavelength | Downtime | Suitable buyer |
| Cryolipolysis (Pmise-F01) | Pinchable, stubborn fat bulges: abdomen, love handles, limbs | Controlled cooling of the vacuum-drawn skin fold at 0~15℃ | None; temporary redness or numbness possible | Clinics and medi-spas that want measurable, hands-free fat reduction |
| Ultrasonic cavitation | Larger, softer fat areas and cellulite | 40KHz ultrasound acting on the hypodermis fat layer | None | Salons and spas that want one affordable all-round slimming platform |
| HIFU lifting | Skin lifting, tightening and contouring on face and body | Focused ultrasound heating deeper tissue layers at precise depths | None to minimal | Clinics adding face lifting and skin tightening to a body-shaping menu |
Fat freezing removes the fat cells themselves, while HIFU firms the tissue that remains, so the two treatments are complementary rather than competing. Many buyers start with the Pmise-F01 for fat reduction and later add a 40K cavitation machine or a HIFU lifting system as their client base grows.
Aesthetic clinics and medi-spas: the treatment is programmable and not technique-dependent - once the handles are placed, no staff time is required - so one operator can run two treatment areas at once while consulting the next client. Precise 1℃ temperature steps let the practitioner document and repeat each protocol.
Beauty salons and slimming studios: fat freezing is a lunchtime procedure with no downtime, which makes it easy to sell as a course. Four handles come as standard, so symmetric areas such as both flanks are finished in a single session and chair time per client stays predictable.
Distributors and wholesale buyers: one model with two handle sizes covers abdomen, buttocks and curved areas alike, simplifying stock and demonstrations. Pmise ships the F01 factory-direct with quotations issued within 12-24 hours, protecting your resale margin.
| Pmise-F01 | |
| Technology | Cryolipolysis + Vacuum + IR |
| Set Temperature | 0~15oC (Step 1oC) |
| Suction Pressure | -0.02MPa~0.09MPa |
| Suction Rate | ≤140L/min |
| Suction Frequency | 1-4 (Adjustable) |
| Cryo Suction Power | 0-8 (Adjustable) |
| IR Power | 0-8 (Adjustable) |
| Working Time | 1~90min (Step 1min) |
| Handles | 2*LP-L1 + 2*LP-S1 |
| LP-L1 Handle Surface | 165*81mm2 |
| LP-S1 Handle Surface | 128*57mm2 |
| Max Power Output | 1400W |
| Display | 12.1'' Color Touch LCD |
| Cooling System | Water + Air + Semiconductor Cooling System |
| Power Supply | 110V/220V±10%, 50/60Hz, 10A |
| Fuse | 250V/10A |
| Net Weight | 55Kg |
Get factory price and full technical specifications for the Pmise-F01 ›
The Pmise-F01 is covered by a one-year warranty from the day you sign for the goods, followed by lifetime maintenance. Technical consulting is answered within 30 minutes and quotations are issued within 12-24 hours, so installation, handle care and daily operation questions never hold your schedule up.
Support comes from an expert team of more than 50 specialists and over 100 technicians, backed by 28 R&D personnel holding 10 patents. Door-to-door service is arranged at least twice a year, and Pmise machines are exported to America, Europe, the Middle East, Africa and Southeast Asia, so overseas buyers receive the same level of service.
Yes. The cryolipolysis method was pioneered at a leading US medical school and has gained FDA approval as well as European CE certification. Controlled cooling crystallizes only the cold-sensitive subcutaneous fat cells, leaving the skin and surrounding tissue unharmed. Typical after-effects are temporary redness, tingling or numbness in the treated area, which resolve completely on their own.
Published clinical research reports a 20-40% reduction of fat in the treated area per session, with about 20% as the average. Trials on love handles showed at least an 11.5% reduction after a single treatment compared with the untreated side. A further reduction can be achieved with an additional session after around two months.
Visible changes typically appear within three weeks of treatment, and the most dramatic results show after about two months. The body continues to flush out the crystallized fat cells for four to six months after the session, so the treated area keeps improving. As long as weight is maintained with normal diet and exercise, long-term results remain stable.
Cryolipolysis is designed as a lunchtime procedure. The vacuum applicator produces a cold, slightly numbing sensation similar to an ice pack, and many clients simply relax or nap during treatment. Clients return to normal activities immediately afterwards; the only common sign is temporarily flushed skin on the treated area for a few hours.
Cryolipolysis freezes localized fat bulges so the fat cells die naturally and are metabolized away, which is ideal for pinchable areas such as love handles and belly rolls. Ultrasonic cavitation instead uses 40KHz sound waves to emulsify fat over larger, softer areas. Many clinics combine both technologies in one slimming program for complementary results.
Pricing depends on handle configuration, order volume and destination. Pmise supplies the Pmise-F01 cryolipolysis fat freezing machine factory-direct to beauty salons, medi-spas and distributors, so you avoid dealer markups. Use the contact form on this page to tell us your country and requirements, and we will send a full quotation with shipping options promptly.
The Pmise-F01 carries a one-year warranty from the day you sign for the machine, followed by lifetime maintenance. Technical consulting is answered within 30 minutes by a support network of more than 100 technicians, and door-to-door service visits are arranged at least twice a year to keep the four handles and the cooling system in reliable condition.
Choose cryolipolysis when clients present pinchable, stubborn fat bulges that resist diet and exercise; the vacuum handles treat two symmetric areas per session with no staff time required. For larger, softer fat layers consider ultrasonic cavitation, and for skin laxity look at HIFU or RF tightening. Many buyers pair the Pmise-F01 with a cavitation machine for a complete slimming menu.
Treatment results vary by skin type, indication and operator settings. Professional operator training is required before clinical use.

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